Citric acid coated magnetite nanoparticles to overcome intrinsic rifampicin resistance in Mycobacterium smegmatis
نویسندگان
چکیده
Methods We have studied the effect of rifampicin on growth of cells, with and without the nanoparticles. Further, cellular uptake of nanoparticles was studied by transmission electron microscopy. Since, permeability barrier and drug efflux are responsible for intrinsic drug resistance, we have performed accumulation and efflux studies on common efflux pump substrate ethidium bromide (EtBr) by semi automated fluorometric method in the presence and absence of nanoparticles.
منابع مشابه
Citric Acid Coated Magnetite Nanoparticles: An Efficient and Reusable Green Catalyst for Rapid Acetylation of Alcohols and Phenols
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